What is sickle cell anaemia (SCA)?
SCA is an inherited blood disorder caused by changes in haemoglobin - the substance in red blood cells that carries oxygen around the body. The condition occurs mostly in black people and less commonly in those of Eastern Mediterranean and Indian origin.
The first signs usually appear after six months of age, and include fatigue, headaches, shortness of breath on exertion, pallor and jaundice.
While the condition is chronic, sudden sickle cell 'crises' can be brought on by infection, cold weather and dehydration, or it may occur for no apparent reason.
How common is it?
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